医院感染病原菌分布及耐药性分析

目的探讨医院感染病原菌分布及耐药情况,提出控制措施. 方法对1998～2003年收住我院所有患者医院感染常见病原菌及耐药情况,进行了回顾性和前瞻性统计分析. 结果 6年中所有医院感染病例共获得各种病原微生物28种3 039株,以革兰阴性细菌占主导共1 459株,占48.01%;革兰阳性细菌明显增多 986株,占32.44%;真菌感染18.99%;这些菌株对临床常用抗生素均有不同程度的耐药性,多重耐药呈增加趋势. 结论降低医院感染发生率,减少医院感染病原菌的增加,合理使用抗生素是今后医院感染工作的一项重要内容.

Nosocomial Infection Pathogens: Their Drug-resistance Analysis and Distribution

OBJECTIVE To investigate the distribution of the nosocomial infection pathogens and their drug-resistance. METHODS Retrospective and prospective epidemiological survey was used on all pathogenic bacteria and their drug-resistance of nosocomial infection among inpatients from 1998 to 2003. RESULTS Of 3 039 clinical isolates, Gram negative organisms accounted for 48.01%,Gram positive ones 32.44%, fungi 18.99%.They resisted to antibiotics at different degrees, and many of them showed multi-resistance. CONCLUSIONS To lower the rate of nosocomial infection, rational use of antimicrobial agents should be emphasized.