| 不同糖耐量人群血清维生素D水平的变化 |
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| 引用本文： | 朱翔,周剑,朱文静,杨光伟,汪兰兰,邵丽洁,王卫东,康冬梅.不同糖耐量人群血清维生素D水平的变化[J].中国临床保健杂志,2016(3):243-245. |
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| 作者姓名： | 朱翔 周剑 朱文静 杨光伟 汪兰兰 邵丽洁 王卫东 康冬梅 |
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| 作者单位： | 1. 安徽医科大学附属省立医院 安徽省立医院，老年内分泌科，合肥 230001;2. 安徽医科大学附属省立医院 安徽省立医院，内分泌科，合肥 230001 |
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| 基金项目： | 安徽省科技计划项目(12010402134) |
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| 摘 要： | 目的探讨血清维生素D在不同糖耐量状态下的变化。方法根据血糖水平将79例受试者分为糖耐量正常组(NC组)、糖耐量减低组(IGT组)和2型糖尿病组(T2DM组),比较不同组间25羟维生素D325(OH)D3]水平及相关代谢指标的差异。结果 25(OH)D3在NC组、IGT组和T2DM组呈递减趋势,NC组、IGT组和T2DM组这三组间在餐后2h血糖、三酰甘油、低密度脂蛋白、体质量指数、稳态胰岛素评价指数(HOMA-IR)和25(OH)D3上差异有统计学意义。进一步行多元回归分析显示,25(OH)D3与HOMA-IR正相关,BMI与HOMA-IR负相关。结论维生素D与糖代谢相关,可能参与了胰岛素抵抗。
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| 关 键 词： | 血糖 葡糖耐量试验 维生素D 葡萄糖代谢障碍 |
| 收稿时间： | 2016/3/25 0:00:00 |
The changes of serum Vitamin D level in people with different glucose tolerance |
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| Zhu Xiang,Zhou Jian,Zhu Wenjing,Yang Guangwei,Wang Lanlan,Shao Lijie,Wang Weidong and Kang Dongmei.The changes of serum Vitamin D level in people with different glucose tolerance[J].Chinese JOurnal of Clinical Healthcare,2016(3):243-245. |
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| Authors: | Zhu Xiang Zhou Jian Zhu Wenjing Yang Guangwei Wang Lanlan Shao Lijie Wang Weidong and Kang Dongmei |
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| Institution: | Department of Senile Endocrinology,the Affiliated Provincial Hospital of Anhui Medical University,Hefei 230001,China,Department of Senile Endocrinology,the Affiliated Provincial Hospital of Anhui Medical University,Hefei 230001,China,Department of Senile Endocrinology,the Affiliated Provincial Hospital of Anhui Medical University,Hefei 230001,China,Department of Senile Endocrinology,the Affiliated Provincial Hospital of Anhui Medical University,Hefei 230001,China,Department of Senile Endocrinology,the Affiliated Provincial Hospital of Anhui Medical University,Hefei 230001,China,Department of Senile Endocrinology,the Affiliated Provincial Hospital of Anhui Medical University,Hefei 230001,China,Department of Senile Endocrinology,the Affiliated Provincial Hospital of Anhui Medical University,Hefei 230001,China and Department of Senile Endocrinology,the Affiliated Provincial Hospital of Anhui Medical University,Hefei 230001,China |
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| Abstract: | Objective To explore the level of serum Vitamin D with different degrees of impaired glucose toler-ance.Methods according to the level of blood glucose,Seventy-nine patients were divided into normal glucose toler-ance group(NC group),impaired glucose tolerance group(IGT group)and T2DMgroup according to the level of blood glucose 25-Hydroxyvitamins D(25(OH)D3)and related metabolic parameters were compared.Results The 25(OH) D3 has the digression trend in the NC group,IGT group and T2DMgroup.There were significant difference on p2hBG, TG,LDL,BMI,HOMA-IR and 25(OH)D3 among three groups.Multiple regression analysis indicates 25(OH)D3 was positively correlated with HOMA-IR and BMI was negatively correlated with HOMA-IR.Conclusion Vitamin D is re-lated to glucose metabolism,and may contribute to insulin resistance. |
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| Keywords: | Blood glucose Glucose tolerance test Vitamin D Glucose metabolism disorders |
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