美托洛尔治疗风湿性心脏病慢性心力衰竭患者的疗效分析

目的探讨美托洛尔治疗风湿性心脏病慢性心力衰竭患者的临床疗效及安全性。方法选取风湿性心脏病慢性心力衰竭患者100例,采用随机数字表法分为研究组和对照组。对照组给予常规治疗,研究组在常规治疗基础上加用美托洛尔。结果与对照组相比,研究组治疗后总有效率显著提高,差异有统计学意义(P0.05)。治疗后,两组患者的SBP、DBP值有显著下降,但在正常值内;两组6 min步行距离与治疗前相比显著增加,LVEF值明显升高,组间比较显示,研究组患者上述指标改善程度明显优于对照组(P0.05)。两组患者在治疗期间均未出现明显的不良反应。结论美托洛尔与常规治疗结合可提高风湿性心脏病慢性心力衰竭患者的临床疗效,有效改善心功能,降低NYHA分级,安全性较高,具有较高的临床价值。

Safety and efficacy of metoprolol in the treatment of rheumatic heart disease patients with chronic heart failure

Objective To discuss the safety and efficacy of metoprolol in the treatment of rheumatic heart dis-ease patients with chronic heart failure.Method 100 cases of patients with rheumatic heart disease patients with chron-ic heart failure were selected,and were divided into research group and control group according to the random number ta-ble,the control group was given routine symptomatic treatment,and the study group received metoprolol on a regular ba-sis.Result Compared with the control group,the total effective rate of the study group was significantly higher and the difference was statistically significant (P <0.05).After treatment,the two groups of patients with SBP,DBP values and 6 min walking distance reduce significantly compared with the pre-treatment,LVEF values increased significantly,the difference was statistically significant (P <0.05),and study the groups in the above indicators improved significantly superior to the control group (P <0.05).After treatment,the two groups of patients with heart rate,cardiothoracic ratio and NYHA classification and treatment of compared decreased significantly,and the difference was statistically signifi-cant(P <0.05),and the index of the study group improved significantly superior to the control group,the difference has statistical significance (P <0.05).There were no obvious adverse reactions in the two groups during the treatment peri-od.Conclusion Combined with metoprolol and conventional therapy can improve the clinical curative effect of rheumat-ic heart disease in patients with chronic heart failure,improve heart function and reduce NYHA class with high security and a high clinical value.