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N-末端脑钠肽原用于急性心力衰竭诊断的价值评估
引用本文:朱长琪,朱道明,高飞,孟令毅,豆正莉,胡承志,孙锟,徐俊,杨静,陆宗海. N-末端脑钠肽原用于急性心力衰竭诊断的价值评估[J]. 中国临床保健杂志, 2016, 0(4): 395-396. DOI: 10.3969/J.issn.1672-6790.2016.04.020
作者姓名:朱长琪  朱道明  高飞  孟令毅  豆正莉  胡承志  孙锟  徐俊  杨静  陆宗海
作者单位:1. 安徽合肥滨湖医院急诊内科,合肥,230061;2. 安徽合肥市第一人民医院急诊内科
摘    要:目的探讨N-末端脑钠肽原对急性心力衰竭诊断的价值。方法选择就诊的急性心力衰竭的患者106例,另选对照组52例,来源于同期因胸闷、气喘、呼吸困难就诊的患者,临床诊断排除急性心力衰竭,分别测定血浆N-末端脑钠肽原浓度,比较不同组患者的血浆N-末端脑钠肽原水平。结果≥75岁人群中,急性心力衰竭组N-末端脑钠肽原(88.41±14.72)pmol/L与对照组N-末端脑钠肽原(33.27±6.61)pmol/L比较,t=18.57,P0.05。75岁人群中,急性心力衰竭组N-末端脑钠肽原(32.73±5.97)pmol/L与对照组N-末端脑钠肽原(6.12±2.51)pmol/L比较,t=27.28,P0.05。结论急性心力衰竭患者N-末端脑钠肽原明显升高,N-末端脑钠肽原对急性心力衰竭诊断有意义。

关 键 词:心力衰竭  利钠肽,脑  呼吸困难
收稿时间:2016-02-27

Value of N-terminal brain natriuretic peptide in the diagnosis of accute heart failure
Zhu Changqi,Zhu Daoming,Gao Fei,Meng Lingyi,Dou Zhengli,Hu Chengzhi,Sun Kun,Xu Jun,Yang and Lu Zonghai. Value of N-terminal brain natriuretic peptide in the diagnosis of accute heart failure[J]. Chinese Journal of Clinical Healthcare, 2016, 0(4): 395-396. DOI: 10.3969/J.issn.1672-6790.2016.04.020
Authors:Zhu Changqi  Zhu Daoming  Gao Fei  Meng Lingyi  Dou Zhengli  Hu Chengzhi  Sun Kun  Xu Jun  Yang  Lu Zonghai
Affiliation:Department of Gastroenterology,Chaohu Hospital of Anhui Medical University,Hefei 238000,China,Department of Gastroenterology,Chaohu Hospital of Anhui Medical University,Hefei 238000,China,Department of Gastroenterology,Chaohu Hospital of Anhui Medical University,Hefei 238000,China,Department of Gastroenterology,Chaohu Hospital of Anhui Medical University,Hefei 238000,China and Department of Gastroenterology,Chaohu Hospital of Anhui Medical University,Hefei 238000,China
Abstract:Objective To explore the value of N-terminal brain natriuretic peptide in the diagnosis of acute heart failure.Methods A total of 158 patients with dyspnea were selected,including 106 patients with acute heart fail-ure and 52 controls and 52 controls with other diease.The N-terminal brain natriuretic peptide were measured and com-pared.Results The N-terminal brain natriuretic peptide of acute heart failure[(88.41 ±14.72)pmol/L ]was signifi-cantly higher than that of the control group[(33.27 ±6.61)pmol/L]in people aged 75 years or older (t =18.57,P <0.05).The N-terminal brain natriuretic peptide of acute heart failure[(32.73 ±5.97)pmol/L]was significantly higher than that of the control group[(6.12 ±2.51)pmol/L](t =27.28,P <0.05).Conclusion The N-terminal brain natri-uretic peptide is significantly increased in patients with acute heart failure,N-terminal brain natriuretic peptide detection has some diagnose value in patients with acute heart failure.
Keywords:Heart failure  Natriuretic peptide,brain  Dyspnea
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