抑郁对择期经皮冠状动脉介入治疗的不稳定型心绞痛患者预后的影响

目的探讨抑郁情绪对择期行经皮冠状动脉介入治疗(PCI)的不稳定型心绞痛(UA)患者预后的影响。方法采用抑郁自评量表(SDS)对217例UA患者择期PCI术前及术后进行抑郁评分,根据评定结果分为抑郁组和非抑郁组(抑郁组82例,非抑郁组135例)。结果 217例行PCI患者,术后抑郁患病率高于术前(37.4%比29.4%,P0.05);术后随访24个月抑郁患者MACE发生率(8.2%比4.3%,P0.05)和累积再住院率(32.7%比20.7%,P0.05)均高于无抑郁患者。结论接受PCI治疗的不稳定型心绞痛患者有相当比例存在不同程度的抑郁情况;术后抑郁程度与患者心血管事件的发生密切相关,而且能影响UA患者预后。

Effect of depression on prognosis of unstable angina pectoris patients received selective percutaneous coronary intervention treatments

Objective To explore the effect of depression on prognosis of unstable angina pectoris(UA)pa-tients who received selective PCI treatments.Methods Self-rating depression scale(SDS)assessments were performed in UA patients(n =217)at pre-and post-selective PCI.The enrolled patients were divided into depression and non-de-pression group according to the result of SDS.Results The prevalence of depression increased after PCI operation (37.4%)compared with that before(29.4%,P <0.05).The MACE rate (8.2%VS.4.3%,P <0.05)and cumula-tive re-hospitalization rate (32.7%VS.20.7%,P <0.05)of depression group were obviously higher than those of non-depression after 24 months follow-up (P <0.05).Conclusion A considerable part of patients with UA treated with PCI have varying degrees of depression,depression levels of postoperative is more closely related to the occurrence of cardiovascular events.