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内毒素、降钙素原在鉴别急性胆管炎及急性胆囊炎中的意义
引用本文:郭美霞,许小兵,金鑫鑫,李敏利,王彬,张晓华. 内毒素、降钙素原在鉴别急性胆管炎及急性胆囊炎中的意义[J]. 中国临床保健杂志, 2016, 0(3): 252-253. DOI: 10.3969/J.issn.1672-6790.2016.03.009
作者姓名:郭美霞  许小兵  金鑫鑫  李敏利  王彬  张晓华
作者单位:南京军区南京总医院,老年病研究中心,南京 210002; 南京军区南京总医院干部消化内科,南京 210002
基金项目:南京军区南京总医院科研基金资助课题(2014069)
摘    要:目的探讨内毒素(ET)、降钙素原(PCT)在鉴别急性胆管炎及急性胆囊炎中的价值。方法检测61例患者血清ET及PCT浓度,其中急性胆管炎组20例,急性胆囊炎组21例,慢性胆管炎组10例,慢性胆囊炎组10例,比较各组间ET及PCT的血清学浓度差异。结果急性胆管炎患者血清中ET、PCT水平较急性胆囊炎组明显升高(t=4.130,P0.05)。急性胆道感染较慢性胆道感染患者ET、PCT血清学水平明显升高(t=9.629,t=5.365,均P0.05)。结论联合检测患者血清ET、PCT浓度可提高急性胆道感染早期确诊率,且ET、PCT与胆道感染炎症程度密切相关。

关 键 词:胆囊炎,急性  胆管炎  内毒素类  神经肽类
收稿时间:2016-02-15

Significance of serum endotoxin,procalcitonin in the differential diagnosis between acute cholangitis and acute cholecystitis
Guo Meixi,Xu Xiaobing,Jin Xinxin,Li Minli,Wang Bin and Zhang Xiaohua. Significance of serum endotoxin,procalcitonin in the differential diagnosis between acute cholangitis and acute cholecystitis[J]. Chinese Journal of Clinical Healthcare, 2016, 0(3): 252-253. DOI: 10.3969/J.issn.1672-6790.2016.03.009
Authors:Guo Meixi  Xu Xiaobing  Jin Xinxin  Li Minli  Wang Bin  Zhang Xiaohua
Affiliation:Gerontology Research Center,Cadres Digestive System Department,General Hospital of Nanjing Military Command,PLA,Nanjing 210002,China,Gerontology Research Center,Cadres Digestive System Department,General Hospital of Nanjing Military Command,PLA,Nanjing 210002,China,Gerontology Research Center,Cadres Digestive System Department,General Hospital of Nanjing Military Command,PLA,Nanjing 210002,China,Gerontology Research Center,Cadres Digestive System Department,General Hospital of Nanjing Military Command,PLA,Nanjing 210002,China,Gerontology Research Center,Cadres Digestive System Department,General Hospital of Nanjing Military Command,PLA,Nanjing 210002,China and Gerontology Research Center,Cadres Digestive System Department,General Hospital of Nanjing Military Command,PLA,Nanjing 210002,China
Abstract:Objective To explore the value of serum the significance of endotoxin(ET),procalcitonin(PCT) in the differential diagnosis between acute cholangitis and acute cholecystitis.Methods Sixty-one patients were col-lected,including 20 acute cholangitis,21 acute cholecystitis,10 chronic cholangitis and 10 chronic cholecystitis.Serum ET and PCT were detected in all subjects.Results Serum ET and PCT of patients with acute cholangitis were signifi-cantly higher than the acute cholecystitis(t =4.130,P <0.05).Serum ET and PCT of patients with acute biliary tract infection were significantly higher than the chronic biliary tract infection(t =9.629,t =5.365,P <0.05).Conclusion Joint detection of ET and PCT can increase the early diagnosis rate of acute biliary tract infection.ET and PCT are closely related to the degree of biliary tract infection.
Keywords:Cholecystitis,acute  Cholangitis  Endotoxins  Neuropeptides
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