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HPLC法测定苦参素注射液中氧化苦参碱的含量
引用本文:孟祥超,马琳. HPLC法测定苦参素注射液中氧化苦参碱的含量[J]. 国际医药卫生导报, 2007, 13(24): 53-55
作者姓名:孟祥超  马琳
作者单位:广东岭南职业枝术学院,广东广州,510663;广州白云山和记黄埔中药有限公司,广东广州,510515
摘    要:目的 建立苦参素注射液的含量测定方法.方法 以氧化苦参碱,氧化槐果碱为对照品,采用高效液相色谱法进行含量测定.结果 氧化苦参碱在0.604~1.412μg范围内呈良好线性关系,r=0.9997,n=6.平均加样回收率为99.7%,RSD=0.26%,阴性对照无干扰.结论 该方法结果准确,重复性好,可以作为苦参素注射液的质量控制方法.

关 键 词:苦参素注射液  氧化苦参碱  氧化槐果碱  HPLC
文章编号:1007-1245(2007)24-0053-03
收稿时间:2007-09-28
修稿时间:2007-09-28

Content Deternination of Oxymatrine in Marine Injection by HPLC
MENG Xiangchao,MA Lin. Content Deternination of Oxymatrine in Marine Injection by HPLC[J]. International Medicine & Health Guidance News, 2007, 13(24): 53-55
Authors:MENG Xiangchao  MA Lin
Abstract:Objective To establish the method for Marine Injection. Methods The Oxymatrine and Oxysophocarprine were detrnined by HPLC. Results The average recovery of Oxymatrine was 100%,and RSD was 0. 078%,respectively. Conclusions The method developed is accurate and the reproducibility is good. The method can be used for quality control of the Marine Injection.
Keywords:MarineInjection Oxymatrine Oxysophocarprine HPLC
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