瑞芬太尼联合丙泊酚在胃镜检查中的应用

目的 研究瑞芬太尼和丙泊酚联合用于胃镜检查的镇静效果和安全性.方法 胃镜检查患者120例给予瑞芬太尼和丙泊酚(镇静组),对照组120例常规操作(不给任何镇静药),比较两组胃镜检查过程中患者的反应和感受,观察其清醒时间及检查前、中、后血压、心率、血氧饱和度变化.结果 镇静组患者98.3%无不适,而对照组为0(P＜0.01).镇静组咳嗽、躁动、恶心呕吐和咽喉不适的发生率分别为1.7%、3.3%、1.7%与0,明显低于对照组(9.2%、26.7%、48.3%与100%)(P＜0.01),检查中有血压下降,但检查结束后迅速恢复至检查前水平.结论 胃镜检查时应用瑞芬太尼和丙泊酚静脉镇静是一种安全、有效的方法 .

Study on painless gastroscopy with rimifentani and propofol

Objective To study the efficacy and safety of sedation in gastroscopy with a combined use of rimifentani and propofol compared to a control,non-sedative group.Methods 120 cases in sedative group were given intravenous rimifentani and propofol.Patients'feeling and discomfort,operator's satisfaction and operative duration were compared with the controI group(n=120,without sedation).The changes of blood pressure,heat rate and blood oxygen saturation were recorded and analysed.Results 118 patients(98.3%)in sedative group and 0 patient(0)in control group did not complain any discomfort and pain duing gastroscopy(P＜0.01).The incidence of cough,restlessness,nausea and vomiting,and guttural discomfort in sedative group(1.7%,3.3%,1.7%,and 0,respectively)was lower as compared with the control group(9.2%,26.7%,48.3%and 100%,respectively,P＜0.01).The blood pressure in sedative group was decreased duing the procedure and recovered after the procedure.Conclusion With intravenous use of rimifentani and propofol,gastroscopy can be performed effectively and safely.