| Serum Lipoprotein (a) Concentration in Patients with Nephrotic Syndrome and Its Clinical Implication |
| |
| 作者姓名： | 杨晓 王惠玲 朱中华 邓安国 |
| |
| 作者单位： | YANG Xiao，WANG Huiling，ZHU Zhonghua，DENG AnguoDepartment of Nephrology，Xiehe Hospital，Tongji Medical University，Wuhan 430022 |
| |
| 摘 要： | Serum lipoprotein(a) Lp(a)] concentration was determined in 42 patients with primary nephrotic syndrome (NS) and the relationships between Lp (a) and plasma lipids, apolipoproteins, serum creatinine (Scr), albumin, urinary proteins (Upro) were also analyzed. The results showed that: (1) serum Lp(a) concentrations in the patients with NS were higher than those in healthy controls;(2) the levels of serum Lp (a) were correlated positively with total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol (VLDL-C), apolipoprotein B (Apo-B), Upros (Upro). It is concluded that the NS patients had the potential risk of suffering from coronary artery disease, glomerular sclerosis and thrombosis. The remission of NS may partially decrease the serum Lp(a) levels. Further studies are needed to explore the prevention and treatment of dislipedemia in patients with NS.
|
| 收稿时间： | 4 November 1997 |
Serum lipoprotein (a) concentration in patients with nephrotic syndrome and its clinical implication |
| |
| Xiao,Yang,Huiling,Wang,Zhonghua,Zhu,Anguo,Deng.Serum Lipoprotein (a) Concentration in Patients with Nephrotic Syndrome and Its Clinical Implication[J].Journal of Zuazhong University of Science and Technology: Medical Edition,1998,18(4):236-238. |
| |
| Authors: | Xiao Yang Huiling Wang Zhonghua Zhu Anguo Deng |
| |
| Institution: | (1) Department of Nephrology, Xiehe Hospital, Tongji Medical University, 30022 Wuhan |
| |
| Abstract: | Serum lipoprotein(a) Lp(a)] concentration was determined in 42 patients with primary nephrotic syndrome (NS) and the relationships between Lp (a) and plasma lipids, apolipoproteins, serum creatinine (Scr), albumin, urinary proteins (Upro) were also analyzed. The results showed that: (1) serum Lp(a) concentrations in the patients with NS were higher than those in healthy controls; (2) the levels of serum Lp(a) were correlated positively with total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol (VLDL-C), apolipoprotein B (Apo-B), Upros (Upro). It is concluded that the NS patients had the potential risk of suffering from coronary artery disease , glomerular sclerosis and thrombosis. The remission of NS may partially decrease the serum Lp(a) levels. Further studies are needed to explore the prevention and treatment of dislipedemia in patients with NS. |
| |
| Keywords: | lipoprotein(a) nephrotic syndrome dislipedemia |
| 本文献已被 CNKI SpringerLink 等数据库收录！ |
|
