REM sleep latency and contingent negative variation in endogenous depression suggestion for a common cholinergic mechanism |
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| Authors: | Marc Ansseau Robert Machowski Georges Franck Martine Timsit-Berthier |
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| Affiliation: | 1. Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel;2. Department of Statistics and Operations Research, The Sackler Faculty of Exact Sciences, Tel Aviv University, Israel;3. The Sagol School of Neurosciences, Tel Aviv University, Israel;1. Centre for Neuropsychiatric Schizophrenia Research and Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Mental Health Centre Glostrup, University of Copenhagen, Denmark;2. Department of Psychology, University of Copenhagen, Denmark;3. Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands;4. Faculty of Health and Medical Sciences, Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark;5. Swartz Center for Computational Neuroscience, Institute for Neural Computation, University of California San Diego, La Jolla, CA, USA. |
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| Abstract: | In a sample of 13 endogenous depressive inpatients, REM (rapid eye movement) latency (recorded over 4 consecutive nights after 2 habituation nights) and contingent negative variation amplitude showed significant relationship, suggesting that both parameters may depend on the same mechanisms, possibly cholinergic. |
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