功能性消化不良的心理社会因素研究

功能性消化不良（FD）患者常伴有焦虑、抑郁、躯体化障碍等心理障碍，心理社会因素可能与FD的发病相关。FD患者多有负性生活事件和生活应激事件的经历。其个性特征和应对方式导致患者表现出更多的心理障碍和消化道症状，出现异常就医行为，从而影响患者的健康相关生活质量。心理社会因素可能通过影响内脏感觉功能、胃运动功能等而影响FD患者的消化道症状。心理干预可改善FD患者的消化不良症状，抗焦虑或抗抑郁治疗对FD亦有一定疗效。

Psychosocial Factors in Functional Dyspepsia

Psychologic obstacles such as anxiety, depression and somatization disorder are commonly seen in patients with functional dyspepsia （FD）. Psychosocial factors may be causally linked to the pathogenesis of FD. Patients with FD often experience negative and stressful life events, their personality trait and coping style may be responsible for more mental disorders, dyspeptic symptoms, and abnormal health care seeking behavior, thus decrease the heahh-related quality of life. Psychosocial factors may adversely affect the perception and motility of gut and thus provoke dyspeptic symptoms in patients with FD. Psychotherapy may improve dyspeptic symptoms in FD patients. Anxiolytics or antidepressants have been shown to be effective in the treatment of FD.