| 原位心脏移植3例 |
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| 引用本文： | 刘季春,徐建军,万于华,饶华庚,王勤,李志平,刘升,吴起才,高涛,陈干.原位心脏移植3例[J].中国组织工程研究与临床康复,2009,13(5):997-1000. |
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| 作者姓名： | 刘季春 徐建军 万于华 饶华庚 王勤 李志平 刘升 吴起才 高涛 陈干 |
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| 作者单位： | 1. 南昌大学第一附属医院心胸外科,江西省南昌市,330006
2. 南昌大学第二附属医院心胸外科,江西省南昌市,330006 |
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| 基金项目： | 江西省卫生厅重点招标项目 |
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| 摘 要： | 2001-0812003-12南昌大学第一附属医院心胸外科分别为3例终末期心脏病患者进行了原位心脏移植,3例供者均为青年男性脑死亡者,供者与受者体质量差异均小于20%.3例受者均采用双腔静脉吻合法,移植后采用环孢素A、强的松及霉酚酸酯联合免疫抑制治疗.3例患者均顺利出院,心功能恢复至NYHA Ⅰ～Ⅱ级,围手术期无感染或严重排斥反应发生.提示良好的心肌保护、完善的围手术期处理以及合理的抗排斥治疗是心脏移植成功的关键.
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| 关 键 词： | 心脏移植 免疫抑制 心肌保护 器官移植 |
Orthotopic heart transplantation in 3 cases |
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| Liu Ji-chun,Xu Jian-jun,Wan Yu-hua,Rao Hua-geng,Wang Qin,Li Zhi-ping,Liu Sheng,Wu Qi-cai,Gao Tao,Chen Gan.Orthotopic heart transplantation in 3 cases[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2009,13(5):997-1000. |
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| Authors: | Liu Ji-chun Xu Jian-jun Wan Yu-hua Rao Hua-geng Wang Qin Li Zhi-ping Liu Sheng Wu Qi-cai Gao Tao Chen Gan |
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| Abstract: | Three cases of terminal stage heart disease received orthotopic heart transplantation at the Department of
Cardiothoracic Surgery, the First Hospital of Nanchang University between August 2001 and December 2003. These three cases
were all female and died of brain death. Body weight difference between donor and recipient was less than 20%. All three cases
underwent superior and inferior vena cave osculation and received immunosuppressive therapy of cyclosporine A, prednisone,
and mycophenolate postoperatively. They were successfully discarded. Heart function recovered to grade Ⅰ-Ⅱ(NYHA). No
infection or serious rejection was found during the surgery. These results indicate that good donor heart preservation,
consummate perioperative processing, and proper immunosuppressiva therapy are the key measures of successful heart
transplantation. |
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