他克莫司软膏加口炎清颗粒治疗糜烂型口腔扁平苔藓的短期疗效评价

目的评价0.03%他克莫司软膏加口炎清颗粒治疗糜烂型口腔扁平苔藓患者的疗效。方法 80例糜烂型口腔扁平苔藓患者,试验组和对照组各40例。试验组用0.03%他克莫司软膏加口炎清颗粒治疗,对照组用0.02%丙酸氯倍他索软膏治疗。结果治疗4周后试验组总有效率为92.50%,对照组为65.00%,差异有统计学意义（χ2=9.038,P〈0.05）。试验组和对照组的不良反应率分别为12.50%（5/40）和17.50%（7/40）,差异无统计学意义（χ2=0.392,P〉0.05）。结论 0.03%他克莫司软膏加口炎清颗粒治疗糜烂型口腔扁平苔藓患者短期疗效可靠。

Efficacy Evaluation of Tacrolimus Ointment and Kouyanqing Granules in Treatment of Erosive Oral Lichen Planus

Objective To evaluate the effect of 0.03% Tacrolimus ointment and kouyanqing granules on treatment of erosive oral lichen planus.Methods Eighty cases of erosive oral lichen planus were randomly divided into control group and observation group,and control group were treated with clobetasol propionate ointment,while observation group were treated with 0.03% tacrolimus ointment and kouyanqing granules.Results After 4-weeks＇ treatment,the total efficacy rate of the observation group is higher than that of the control group,with significant difference.Conclusion Kouyanqing granules and 0.03% tacrolimus ointment has good curative effect on treatment of erosive oral lichen planus.