| P^53蛋白在42例胃癌的表达与分析 |
| |
| 引用本文： | 浣孝强,姜海行.P^53蛋白在42例胃癌的表达与分析[J].广西医科大学学报,1996,13(1):8-11. |
| |
| 作者姓名： | 浣孝强 姜海行 |
| |
| 作者单位： | 广西医科大学病理学教研室 |
| |
| 摘 要： | 应用免疫化技术检测了４２例胃癌标本Ｐ＾５３蛋白的异常表达。结果显示：Ｐ＾５３蛋白表达的阳性率为３３．３３％（１４／４２），癌旁粘膜及癌间质Ｐ＾５３蛋白表达为阴性。
|
| 关 键 词： | 胃肿瘤 P53蛋白 免疫组化 |
THE EXPRESSION OF P~(53) PROTEIN IN 42 CASES OF GASTRIC CANCER |
| |
| Huan Xiaoqiang, Feng Zhengbo, Li Fancai, et al.THE EXPRESSION OF P~(53) PROTEIN IN 42 CASES OF GASTRIC CANCER[J].Journal of Guangxi Medical University,1996,13(1):8-11. |
| |
| Authors: | Huan Xiaoqiang Feng Zhengbo Li Fancai |
| |
| Abstract: | The expression of p53 protein was studied in 42 cases of gastric cancer byimmunohistochemical technioue.The results are as follows:In all cases examined.33.33 %(14/42)showed positive p53 protein expression,In the adjacent mucosa and in the tumorstroma the expression of p53 protein was negative.The positive rate of p53 expression corre. lated with the depth of infiltration(P<0.05)and lympth node metastases(P<0.01)ofgastriccancer.No relationship could be found between the rate of p53 expression and the histologictype and degree of differentiation of gastric cancer.These results suggest that in endoscopicbiopsy,one should suspect malignancy with positive p53 protein staining,and that theoverexpressiOn of p53 protein may suggest deep penetration and metastases of thecancer.Hence,immunohistochemical staining for P53 protein expression may be useful in de-termining the development and prognosis of gastric cancer, |
| |
| Keywords: | gastric cancer p53 protein immunohistochemistry |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
