Observations on Heinz Bodies in Normal and Splenectomized Rabbits |
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| Authors: | ROTHBERG, HARVEY CORALLO, LEON A. CROSBY, WILLIAM H. |
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| Affiliation: | 1 Department of Hematology, Walter Reed Army Institute of Research, WalterReed Army Medical Center, Washington, D. C.
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| Abstract: | The disappearance from the circulation of Heinz bodies, produced byincubation of blood with phenylhydrazine, was studied in normal andsplenectomized rabbits. In the intact animal, red cells damaged by thisprocedure are removed largely by the spleen. In both intact and splenectomized rabbits, the Heinz bodies are withdrawn from the circulation byremoval in toto of the red cells containing them. Submitted on January 9, 1959 Accepted on June 1, 1959 |
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