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正交试验法研究酸牛奶制石决明的炮制工艺
引用本文:陈少丽,王磊磊,张志杰,张艳玲,朝格图.正交试验法研究酸牛奶制石决明的炮制工艺[J].中国民族医药杂志,2012,18(9):47-50.
作者姓名:陈少丽  王磊磊  张志杰  张艳玲  朝格图
作者单位:1. 内蒙古大学化学化工学院,呼和浩特,010021
2. 中国中医科学院中药研究所,北京,100700
基金项目:内蒙古大学高层次人才引进科研启动项目(Z20100118)
摘    要:目的:对酸牛奶制石决明的炮制工艺进行优化。方法:采用正交试验法,以酸牛奶用量、煎煮时间、干燥温度、干燥时间为条件,以炮制品中总Ca2+含量、水煎液Ca2+含量、人工胃液Ca2+溶出量为指标,利用原子吸收分光光度法对其分别进行测定,对酸牛奶制石决明的炮制工艺进行了研究。结果:对测定结果分别进行直观分析和方差分析,可知,在酸牛奶炮制石决明的工艺条件中,酸牛奶用量A、干燥时间D对结果会产生主要的影响,而煎煮时间B、干燥温度C对测定Ca2+含量的影响比较小。结论:确定酸牛奶炮制石决明的最佳工艺条件为:石决明与酸牛奶用量(g:g)为1:1,煮制6h,于180℃烘干1h,为酸牛奶制石决明炮制工艺的优化提供了参考。

关 键 词:石决明  酸牛奶  炮制工艺  Ca2+含量

Process Optimization for Shijueming Concocted by Sour Milk
Chen Shao-li , Wang Lei-lei , Zhang Zhi-jie , Zhang Yan-ling , Tsogt.Process Optimization for Shijueming Concocted by Sour Milk[J].Journal of Medicine & Pharmacy of Chinese Minorities,2012,18(9):47-50.
Authors:Chen Shao-li  Wang Lei-lei  Zhang Zhi-jie  Zhang Yan-ling  Tsogt
Institution:Chen Shao - li Wang Lei - lei Zhang Zhi - jie Zhang Yan- ling Tsogt ( 1. College of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China; 2. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China)
Abstract:Objective:Optimize the concocting process of Shijueming by sour milk. Methods:In this thesis, the orthogonal experi- mental design method, four factors, the amount of sour milk ( A), boiling time ( B ), drying temperature (C) and drying time (D) were selected, the atomic absorption spectrophotometry was use to determine the Ca2 + content, and the total Ca2 + content, Ca2 + content in decoction and Ca2 + release from artificial gastric juice. Results: The res Lt shows that the amount of sour milk (A) and drying time (D) are the main factors, and boiling time ( B ) and drying temperature (C) affects less for the concocting process. Conclusion: The optimum condition is that Shijueming and sour milk consumption (g: g) 1 : 1, boil for 6h and dry at 180℃ for 1 h. This study supplies a scientific reference for the optimization of the Mongolian shijueming processing technology.
Keywords:Shijueming  Sour Milk  Concocting Process  Ca2+ content
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