| 急性淋巴细胞白血病并发肿瘤溶解综合征7例 |
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| 引用本文： | 高飞.急性淋巴细胞白血病并发肿瘤溶解综合征7例[J].白血病．淋巴瘤,2000,9(5). |
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| 作者姓名： | 高飞 |
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| 作者单位： | 福建省立医院!福建福州350001 |
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| 摘 要： | 目的 :探讨急性淋巴细胞白血病 (AL L )患者化疗后发生肿瘤溶解综合征 (TL S)的临床特征。方法 :对 7例化疗发生 TL S的 AL L患者进行各项生化指标的分析。结果 :TL S患者表现为高尿酸血症、高血钾、高血磷、低血钙 ,并有不同程度的肾功能损伤 ,其中 1例发生了急性肾功能不全。用别嘌呤醇及静脉碱化利尿后 ,6例短期内血生化指标恢复正常。1例死于心衰。结论 :早期诊断并及时给予别嘌呤醇及静脉碱化利尿是治疗 TL S的关键
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| 关 键 词： | 肿瘤溶解综合征 白血病 淋巴细胞 急性 |
ACUTE LYMPHOBLASTIC LEUKEMIA COMPLICATEDL WITH TUMOR LYSIS SYNDROME:SEVEN CASES REPORT |
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| GAO Fei,SONG Tuan yue Fujian Provencial Hospital.ACUTE LYMPHOBLASTIC LEUKEMIA COMPLICATEDL WITH TUMOR LYSIS SYNDROME:SEVEN CASES REPORT[J].Journal of Leukemia & Lymphoma,2000,9(5). |
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| Authors: | GAO Fei SONG Tuan yue Fujian Provencial Hospital |
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| Abstract: | Objective:To report seven acute lymphoblastic leukmia(ALL) patients who developed tumor lysis syndrome(TLS) after initial chemotherapy.Methods:The clinical features and blood biochemical changes of seven patients with TLS were analysed.Results:TLS was characterized by hyperuricemia,hyperkalemia,hyperphosphatemia and hypocalcemia.After allopurinol therapy and alkalinization of urine,the blood biochemical parameter became normalization in six cases.Conclusion:TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine. |
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| Keywords: | Tumor lysis syndrome Leukemia Lymphoblastic Acute |
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