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Asymptomatic circulation of HEV71 in Norway
Authors:Witsø Elisabet  Palacios Gustavo  Rønningen Kjersti S  Cinek Ondrej  Janowitz Diana  Rewers Marian  Grinde Bjørn  Lipkin W Ian
Affiliation:Norwegian Institute of Public Health, Oslo, Norway.
Abstract:Widespread circulation of human enterovirus 71 was discovered in a prospective study of fecal samples obtained from healthy Norwegian children. Molecular characterization of the virus determined that it belonged to genotype C1. Complete sequencing of this strain, HEV71 804/NO/03, revealed differences in the 5'UTR and polymerase with respect to more pathogenic genotypes that may explain its reduced neurovirulence.
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