Asymptomatic circulation of HEV71 in Norway |
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Authors: | Witsø Elisabet Palacios Gustavo Rønningen Kjersti S Cinek Ondrej Janowitz Diana Rewers Marian Grinde Bjørn Lipkin W Ian |
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Affiliation: | Norwegian Institute of Public Health, Oslo, Norway. |
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Abstract: | Widespread circulation of human enterovirus 71 was discovered in a prospective study of fecal samples obtained from healthy Norwegian children. Molecular characterization of the virus determined that it belonged to genotype C1. Complete sequencing of this strain, HEV71 804/NO/03, revealed differences in the 5'UTR and polymerase with respect to more pathogenic genotypes that may explain its reduced neurovirulence. |
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