Reduction of bladder contractility after alpha-adrenergic blockade and after ganglionic blockade |
| |
Authors: | Paul E. KaplanM.D. F.A.C.P. JOhn B. NAnninga |
| |
Affiliation: | Rehabilitation Institute of Chicago;and Northwestern University, Department of Urology, Chicago, IL, USA. |
| |
Abstract: | Seven spinal cord injured patients were evaluated with cystometry bladder, electromyography, and pressure profiles of the external urethral sphincter before and after phenoxybenzamine administration. Seven more patients were evaluated before and after mecamylamine administration. Both drugs reduced the contractility of the bladder. The reduction of bladder contractility may reflect decreased sympathetic stimulation to the bladder. Bladder electric potentials reflect the intrinsic tone of the detrusor muscle. |
| |
Keywords: | Bladder contractility alpha-adrenergic blockade ganglionic blockade |
|