A comparison of the mean signal change method and the voxel count method to evaluate the sensitivity of individual variability in visuospatial performance |
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| Authors: | Soon-Cheol Chung Jin-Hun Sohn Bongsoo Lee Gye-Rae Tack Jeong-Han Yi Ji-Hye You Ji-Hun Kwon Hyun-Jun Kim Soo-Yeol Lee |
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| Affiliation: | 1. Department of Biomedical Engineering, Research Institute of Biomedical Engineering, College of Biomedical & Health Science, Konkuk University, 322 Danwall-dong, Chungju, Chungbuk 380-701, South Korea;2. Department of Psychology, Chungnam National University, Daejon, South Korea;3. Department of Obstetrics & Gynecology, Konkuk University, Chungju, South Korea;4. Department of Biomedical Engineering, Kyunghee University, Soowon, South Korea |
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| Abstract: | This study compared the mean signal change method and the voxel count method in evaluating the sensitivity of individual variability in visuospatial performance using functional Magnetic Resonance Imaging (fMRI). Sixteen right-handed male college students (mean age 23.2 years) participated in this study as subjects. Functional brain images were scanned with a 3T MRI single-shot EPI method during a visuospatial task. No correlation was found between visuospatial performance and the number of activated voxels in the activated brain areas. Significant positive correlations, however, were found between visuospatial performance and the mean signal changes of activated voxels in the parietal, frontal and other areas. In conclusion, the mean signal change is more sensitive to individual variability in visuospatial performance than the number of activated voxels. |
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| Keywords: | Mean signal change Voxel count BOLD fMRI Visuospatial performance |
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