CD62P分子在高血压患者中的表达变化

目的：研究CD62P分子在不同级别高血压患者中的表达变化。方法：120例高血压患者,按血压水平分为高血压1级组（60例）和高血压3级组（60例）,分别测定两组患者的血清CD62P分子和血小板膜CD62P分子的表达。结果：高血压病1级组患者血清CD62P表达明显低于高血压病3级组[（2.88±0.64）ng/ml∶（3.78±0.45）ng/ml,P〈0.05];高血压病1级组患者血小板膜CD62P表达明显低于高血压病3级组[（3.35±0.24）ng/ml∶（5.78±0.32）ng/ml,P〈0.05]。结论：高血压1级组患者的血清和血小板膜CD62P表达显著低于高血压3级组患者。

Expression of CD62P molecule in patients with hypertension

Objective：To study the change of CD62P molecule expression in patients with different stages of hypertension.Methods：The 120 hypertension patients were average divided into hypertension stage 1 group and hypertension stage 3 group.The levels of CD62P expression in serum and platelet membrane were detected in all hypertension patients.Results：Level of serum CD62P in patients with hypertension stage 1 group was[（2.88±0.64） ng/ml and hypertension stage 3 group was（3.78±0.45） ng/ml.Level of serum CD62P in hypertension stage 1 group was significantly lower than that of hypertension stage 3 group（P0.05）.Expression rate of platelet membrane CD62P in patients of hypertension stage 1 group was [（3.35±0.24）ng/ml and hypertension stage 3 group was（5.78±0.32） ng/ml.Expression rate of platelet membrane CD62P in hypertension stage 1 group was significantly lower than that of hypertension stage 3 group（P0.05）.Conclusion：The levels of serum and platelet membrane CD62P in hypertension stage 1 group are significantly lower than that of hypertension stage 3 group.