Analysis of gastric cancer with cDNA microarray |
| |
Authors: | Haraguchi Naotsugu Inoue Hiroshi Mimori Koshi Tanaka Fumiaki Utsunomiya Tohru Yoshikawa Kouji Mori Masaki |
| |
Affiliation: | Department of Surgery and Molecular Oncology, Medical Institute of Bioregulation, Kyushu University, 4546 Tsurumihara, 874-0838 Beppu, Japan. |
| |
Abstract: | Recent advances in cDNA microarray techniques have enabled us to study the expression of many genes simultaneously. As gastric cancer remains one of the most common cancers in Japan, we studied gene expression profiles in gastric cancer by cDNA microarray analysis to determine if it would be clinically useful. We demonstrated two points. First, cDNA microarray might be useful as a prognostic indicator. However, there remain several important problems to be solved and these are discussed. Second, laser microdissection plus cDNA microarray might be useful in determining the specific genes that correlate to cancer metastasis or histological subtype. We review the pros and cons for cDNA microarray analysis in the context of gastric cancer. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|