| 精囊原发性Burkitt淋巴瘤1例报告并文献复习 |
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| 引用本文： | 欧阳俊,印洪林,陆珍凤,周航波,周晓军. 精囊原发性Burkitt淋巴瘤1例报告并文献复习[J]. 中华男科学杂志, 2009, 15(8): 733-737 |
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| 作者姓名： | 欧阳俊 印洪林 陆珍凤 周航波 周晓军 |
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| 作者单位： | 南京军区南京总医院病理科,江苏,南京,210002 |
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| 摘 要： | 目的:报告精囊原发性Burkitt淋巴瘤(BL)的临床病理特征。方法:对1例精囊原发性BL的临床特征、组织学、免疫组织化学和原位分子杂交进行观察,并结合文献探讨其病理形态及鉴别诊断。结果:本例临床表现以尿频和排尿困难为特征,发病2个月后出现腹股沟淋巴结肿大。影像学显示病灶精囊呈低密度阴影,组织学呈弥漫单一性中等大小肿瘤细胞浸润性生长伴肿瘤性坏死,核分裂易见并有"星空"图象。免疫标记肿瘤细胞表达CD10、CD20、CD79α和Bcl-6,而CD3、CD5、CD23、MPO、Bcl-2、CyclinD1和TdT缺乏表达,肿瘤细胞Ki-67增殖指数>95%,原位杂交检测肿瘤细胞EBER阳性。结论:精囊原发性BL是一种非常罕见的高度恶性的肿瘤,病程进展快,诊断时应除外精囊外BL累及,确诊依赖病理组织学和实验室检查,并需要与精囊或前列腺发生的弥漫性大B细胞性淋巴瘤、淋巴母细胞淋巴瘤和小细胞癌鉴别。
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| 关 键 词： | 精囊 Burkitt淋巴瘤 前列腺 免疫组织化学 |
Primary Burkitt Lymphoma of the Seminal Vesicle: A Case Report and Review of the Literature |
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| OUYANG Jun,YIN Hong-lin,LU Zhen-feng,ZHOU Hang-bo,ZHOU Xiao-jun. Primary Burkitt Lymphoma of the Seminal Vesicle: A Case Report and Review of the Literature[J]. National journal of andrology, 2009, 15(8): 733-737 |
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| Authors: | OUYANG Jun YIN Hong-lin LU Zhen-feng ZHOU Hang-bo ZHOU Xiao-jun |
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| Affiliation: | (Department of Pathology, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China) |
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| Abstract: | Objective:To investigate the clinicopathological features of primary Burkitt lymphoma of the seminal vesicle.Methods:We reported the clinical characteristics,histological changes and the results of immunohistochemical staining and molecular in situ hybridization of 1 case of primary Burkitt lymphoma of the seminal vesicle.We also reviewed the related literature and studied the pathomorphological characteristics and differential diagnosis of the tumor.Results:The characteristic manifestations of the patient ... |
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| Keywords: | seminal vesicle Burkitt lymphoma prostate gland immunohistochemistry |
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