341例儿童传染性单核细胞增多症临床分析

目的:了解儿童传染性单核细胞增多症的临床特点,探讨胆囊壁增厚与疾病严重程度的关系.方法:采用回顾性研究方法对本院收治的341例传染性单核细胞增多症病例进行分析.结果:发热341例(100%),咽峡炎330例(96.8%),淋巴结肿大307例(90.0%),肝肿大272例(79.8%),脾肿大171例(50.1%),眼睑浮肿147例(43.1%),皮疹72例(21.1%),严重鼻塞71例(20.8%),肝功能异常144例/205例(70.2%),胆囊壁增厚34例/198例(17.2%).血小板减少和胆囊壁增厚率增高,则肝功能异常的程度增高(P＜0.05).结论:EB病毒引起的传染性单核细胞增多症,临床表现复杂多样,病情轻重不一,血小板减少和胆囊壁增厚往往提示肝功能损害较重.

Clinical Analysis of 341 Cases with Infectious Mononucleosis(IM)

Objective:To study the clinical characteristics of acute infectious mononucleosis.To assess any relationship between gallbladder wall thickening(GBWT)and the severity of disease.Methods:The 341 cases with infectious mononucleosis treated from January 1,2000 to December 31,2003 were retrospectively studied and analysed.Results:The symptoms of IM were divers,the most common symptom was fever(100%)and followed by tonsilloparyngitis(96 8%),lymphadenopathy(90 0%),enlargement of liver(79 8%),splenomegaly(50 1%),eyelid edema(43 1%),skin eruption(21 1%),serious obstruction in the nose(20 8%),hepatic insufficiency(70 2%),GBWT(17 2%),the cases with hepatic insufficiency in the patients with GBWT were significantly more than those in patients without GBWT,( P <0 05).Conclusion:The clinical manifestations of infectious mononucleosis by EBV infection in children were diverse,pediatrist should comprehensively analyze the clinical data.GBWT in infectious mononucleosis may be a sign of the severity of the illness. [