| 京玉清肝胶囊抗鸭乙肝病毒效应及其机制探讨 |
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| 引用本文： | 张洪泉,刘云. 京玉清肝胶囊抗鸭乙肝病毒效应及其机制探讨[J]. 中国现代中药, 2006, 8(2): 8-10 |
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| 作者姓名： | 张洪泉 刘云 |
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| 作者单位： | 1. 扬州大学医药研究所,江苏,扬州,225001
2. 北京万赛生物医药技术发展有限公司,北京,100089 |
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| 摘 要： | 目的：研究京玉清肝胶囊抗鸭乙型肝炎病毒（DHBV）的作用。方法：采用重庆麻鸭乙型肝炎动物模型口服灌胃，治疗28d，停药观察7d，检测用药前、后血清中DHBV DNA的改变情况及肝脏病理改变。结果：京玉清肝胶囊用药28d后鸭血清中的DHBV DNA降低有显著意义（P〈0．05），停药7d后未出现反跳。结论：京玉清肝胶囊在鸭体内有抑制鸭乙型肝炎病毒DNA的作用且停药后无反跳。
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| 关 键 词： | 京玉清肝胶囊 抗鸭乙肝病毒 |
| 收稿时间： | 2006-01-04 |
| 修稿时间： | 2006-01-04 |
Effect and Its Mechanism of Jingyu Qinggan Capsule on Duck Hepatitis B Virus in Vitro |
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| Zhang Hongquan and Liu Yun. Effect and Its Mechanism of Jingyu Qinggan Capsule on Duck Hepatitis B Virus in Vitro[J]. Modern Chinese Medicine, 2006, 8(2): 8-10 |
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| Authors: | Zhang Hongquan and Liu Yun |
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| Affiliation: | Medical and Pharmacological Institute of Yangzhou University, Yangzhou Jiangsu 225001, China;Beijing Wansai Biomedical Science Co., Ltd, Beijing 100089, China |
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| Abstract: | Objective: To study the therapeutic effect of jingyu qinggan capsule against duck hepatitis B virus(DHBV) in vitro. Methods: The Chongqing duck hepatitis B animal model was treated with Jingyu Qinggan capsuleby consecutive gastric infusion for 28 days. After stopping the treatment for 7 days, DHBV DNA in serum and thepathological transformation in liver were observed. Results: Jingyu qinggan capsule could significantly reduce theDHBV DNA level after 28 days of administration and couldn't observe the rebound after 7 days of suspension.Conclusion: Jingyu Qinggan capsule have the function on abti-DHBV in duck. |
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| Keywords: | Jingyu qinggan capsule Duck hepatitis B virus(DHBV) |
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