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| 856株下呼吸道感染肠杆菌科细菌的ESBLs检测及相关分析 | |
| 引用本文： | 陶勇,姚杰,贾建安,吕晴.856株下呼吸道感染肠杆菌科细菌的ESBLs检测及相关分析[J].临床肺科杂志,2009,14(5):614-615. |
| 作者姓名： | 陶勇 姚杰 贾建安 吕晴 |
| 作者单位： | 1. 解放军第105医院医务处,合肥,230031 2. 安徽医科大学第二附属医院检验科 3. 解放军第105医院检验科 4. 合肥市红十字中心血站检验科 |
| 摘 要： | 目的分析产ESBLs的下呼吸道感染的常见肠杆菌科细菌的耐药性及耐药特点，以及患者感染产ESBLs菌的危险因素，为临床用药提供参考。方法对我院2007年2月～2008年8月分离的下呼吸道感染的肠杆菌科细菌用梅里埃ATB152微生物分析仪进行鉴定，检测ESBLs表型和药物敏感试验。结果在检测的肠杆菌科细菌中，ESBLs总阳性率为41．3％，大肠埃希菌、肺炎克雷伯菌和阴沟肠杆菌的产酶率分别为42．0％、52．0％和35．1％，产ESBLs的菌株对除碳青酶烯类之外的抗菌药物耐药率明显高于非产酶株，其中多数差异有统计学意义（P〈0．05）。结论感染产ESBLs菌的危险因素为长期使用三代头孢菌素、使用免疫抑制剂、ICU患者、做过导尿插管、动过大手术、患慢性消耗性疾病的患者。治疗产ESBLs菌引起的感染，应选用亚胺培南、或β-内酰胺酶抑制剂的复合物，慎用三代头孢。 |
| 关 键 词： | 呼吸道感染 超广谱β-酰胺酶 耐药率 危险因素 |
Lower respiratory tract infection of the Enterobacteriaceae bacteria ESBLs detection and analysis of relevant factors |
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| TAO Yong,YAO Jie,JIA Jian'an,LV Qing.Lower respiratory tract infection of the Enterobacteriaceae bacteria ESBLs detection and analysis of relevant factors[J].Journal of Clinical Pulmonary Medicine,2009,14(5):614-615. | |
| Authors: | TAO Yong YAO Jie JIA Jian'an LV Qing |
| Institution: | TAO Yong1,YAO Jie2,JIA Jian'an3,LV Qing4 1.Department of Medical Affairs,No.105 Hospital of PLA,Hefei 230031,China,2.Department of Clinical Laboratory,the Second Affiliated Hospital of Anhui Medical University,Hefei 230601,3.Department of Clinical Laboratory,Hefei 132011,4.Department of Clinical Laboratory,Red Cross Blood Center of Hefei |
| Abstract: | Objective Analysis of the production of ESBLs lower respiratory tract infections common Enterobacteriaceae bacteria resistance and resistance characteristics,as well as ESBLs producing bacteria infection in patients with risk factors for clinical use for reference.Methods In February 2007 to August 2008 the bacteria of the Enterobacteriaceae separation from the lower respiratory tract infection with BIOMERIEUX ATB1525 microbial analyzer to identify,detect ESBLs phenotype and drug sensitivity tests.Results I... |
| Keywords: | respiratory tract infections ESBLs resistance rate risk factors |
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