小儿止咳颗粒治疗咳嗽变异性哮喘的临床观察

目的:评价小儿止咳颗粒治疗小儿咳嗽变异性哮喘的临床疗效。方法:以小儿止咳颗粒治疗90例咳嗽变异性哮喘患儿,设立氨茶碱 开瑞坦对照组,比较两组患儿治疗3天、5天、7天后的有效率。对于5岁以上患儿,比较两组治疗前后最大呼气峰流速(PEFR)。结果:治疗3天、5天后的有效率比较,观察组高于对照组,有显著性差异(P<0.05,P<0.01);治疗7天的有效率比较,两组无显著性差异(P>0.05),提示观察组起效较对照组快;经过1周治疗,两组PEFR均较治疗前有所改善,自身前后比较有显著性差异(P<0.05),但两组间无显著性差异(P>0.05)。结论:(1)小儿止咳颗粒对咳嗽变异性哮喘患儿的疗效显著,起效时间优于氨茶碱 开瑞坦组;(2)小儿止咳颗粒可以改善咳嗽变异性哮喘患儿的PEFR值。

Clinical Observation of Children Couph Pellet in Tearing 92 Cases of Cough Variant Asthma

Objective:To research the functional mechanist of Children Cough Pellet(CCP)and to evaluate its clinical efficacy.Methods:60 children were threated with CCP,and give the comparing group with Aminophylline and Clarityne.Comparing the two group's efficacy after treated 3-day,5-day,7-day.As to the children more than 5 years old,compare the two group's peak respiration flow rate(PEFR)before the treatment.Results:Comparing the two groups of 3-day and 5-day treatment,the effective rate of the observing group is higher than that of the comparing group,and the difference is remarkable(P<0.05);Comparing the effective rate of two groups of 7-day,there is no remarkable between the two groups(P>0.05),which indicates the effect of observing group was faster.After a week treating,PEFR of the two groups both ameliorate than before,and there is remarkable difference between before and after the treatment(P<0.05);But there is not remarkable difference between the two groups(P>0.05).Conclusions:(1)The children cough pellet is remarkable effective to the CVA child,and the effect-time is superior to the "aminophylline and clarityne"group.(2)The children cough pellet can improve the PEFR of patient.