扶正培本药物治疗恶性肿瘤的现代研究

扶正培本药物是指能补充与调节人体气血阴阳之不足,改善脏腑功能,增强体质,提高机体免疫功能,用于治疗肿瘤虚证的一类药物,它是扶正培本法在临床应用的具体体现。研究表明,扶正培本药物具有增强和调节机体免疫功能、保护骨髓及提高机体造血机能、增加消化吸收功能,改善物质代谢、阻止基因突变、抑制肿瘤细胞增殖、诱导分化、促使肿瘤细胞凋亡、抗肿瘤侵袭与转移、抑制肿瘤血管形成及肿瘤细胞端粒酶活性等多种作用,其发挥的扶正作用可能是多途径、多靶点联合协同作用的结果。然而由于扶正培本药物的多样性,各种不同类别的扶正药物又有其自身的特异性,其确切的作用机制尚有待进一步深入研究。

Contemporary study of strengthening body resistance and archaeus herbs on malignant tumor

Strengthening body resistance and archaeus herbs are those medicines used on asthenia syndrome of tumor,which can harmonize yin and yang,replenish deficiency of qi and blood,and improve entrails function,enhance physical capacity,and improve immunity function.They are intimate manifestation of strengthening body resistance and archaeus method on clinic.Study shows that strengthening body resistance and archaeus herbs have many effects,such as improving and adjusting immunity function,protecting bone marrow,improving haematogenesis function,raising digest and absorb function,improving substance metabolism,preventing gene mutation,inhibiting tumor cell proliferation,inducing tumor cell differentiation or apoptosis,resisting tumor invasion and metastasis,inhibiting formation of tumor vessel and activity of telomerase,etc.It's possibly the result of synergistic effect by multi-pathway and multi-target.Because strengthening body resistance and archaeus herbs are of variety and different herbs have different specificity,further research is needed to reveal the precise mechanism of them.