| 中药复方足疡平软膏对糖尿病大鼠感染创面抗菌作用实验研究 |
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| 引用本文： | 周秀珍,罗曼,吴军,蔡景英,代贵凤,刘群,柳亢宗. 中药复方足疡平软膏对糖尿病大鼠感染创面抗菌作用实验研究[J]. 中华医院感染学杂志, 2006, 16(11): 1207-1209 |
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| 作者姓名： | 周秀珍 罗曼 吴军 蔡景英 代贵凤 刘群 柳亢宗 |
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| 作者单位： | 武汉市第三医院,湖北,武汉,430060 |
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| 基金项目： | 湖北省武汉市卫生局资助项目 |
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| 摘 要： | 目的观察局部外治复方中药足疡平的抗菌作用,为临床应用提供实验依据。方法30只大鼠随机分为3组,即足疡平组、血小板源性生长因子凝胶组、空白组,每组10只大鼠,将足疡平用于糖尿病大鼠感染创面,动态对照观察局部细菌总量和G-菌量变化及创面愈合指标。结果足疡平组实验第3、7天总菌量、G-菌量均显著低于第1天,亦低于对照组;其创面愈合速率快于对照组。结论中药复方制剂外治糖尿病创面具有良好的抗菌作用,值得临床应用。
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| 关 键 词： | 糖尿病 创面 中药 足疡平 细菌 |
| 文章编号： | 1005-4529（2006）11-1207-03 |
| 收稿时间： | 2006-02-20 |
| 修稿时间： | 2006-05-15 |
Antibacterial Effect of Foot-ulcer-cure Ointment on Ulceration of Diabetic Rat:An Experimental Study |
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| ZHOU Xiu-zhen,LUO Man,WU Jun,CAI Jing-ying,DAI Gui-feng,LIU Qun,LIU Kang-zong. Antibacterial Effect of Foot-ulcer-cure Ointment on Ulceration of Diabetic Rat:An Experimental Study[J]. Chinese Journal of Nosocomiology, 2006, 16(11): 1207-1209 |
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| Authors: | ZHOU Xiu-zhen LUO Man WU Jun CAI Jing-ying DAI Gui-feng LIU Qun LIU Kang-zong |
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| Affiliation: | Wuhan Third Hospital, Wuhan, Hubei 430060, China |
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| Abstract: | OBJECTIVE To observe the antibacterial effect of the foot-ulcer-cure ointment a compound traditional chinese materia medica(TCMM) preparation manufatured on ulceration of(diabetic) rat,in order to give the basis for clinical treatment.METHODS The total(amount) of bacteria and amount of G~-bacteria and the quota of wound healing after the ointment given to the ulceration surface of(diabetic) rats were observed.RESULTS At the third and seventh day,the total amount of(bacteria) and amount of G~-bacteria of the experiment group were remarkably less than the first day and the control group;the speed rate of the wound healing was faster than the control one.CONCLUSIONS The foot-ulcer-care ointment of TCMM has excellent antibacterial functions to diabetic ulceration.It is worth for popularization. |
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| Keywords: | Diabetes mellitus Ulceration Tradional Chinese materia medica(TCMM) Foot-ulcer-cure ointment Bacteria |
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