保胆取石术后结石复发相关因素及长期随访分析

目的探讨保胆取石术后结石复发情况及复发的高危因素。方法选择2000年1月—2006年1月我院收治的148例行保胆取石术的胆囊结石患者,随访6～12年观察结石复发率和复发的高危因素。结果 148例患者中54例结石复发,总复发率为36.49%。Logistic回归分析显示结石家族史、体质指数和糖尿病是胆结石复发的独立危险因素。结论保胆取石术是一种有效治疗胆囊结石的方法,但对伴有代谢综合征的胆结石患者应慎用保胆取石手术或术后采取防石药物治疗。

Long-Term Observation on Recurrence of Cholecystolithiasis after Minimally Invasive Cholecystolithotomy

Objective To observe the recurrence rate of cholecystolithiasis after minimally invasive cholecystolithotomy and to analyze its risk factors.Methods 148 cholecystolithiasis patients admitted from January 2000 to January 2006 and treated with minimally invasive cholecystolithotomy were followed up for six to twelve years to observe recurrence rate and to analyze risk factors.Results 54 cases out of the 148 patients recurred and the overall recurrence rate was 36.49%.Logistic regression analysis showed that family history of cholecystolithiasis,body mass index(BMI) and diabetes mellitus were independent risk factors for the recurrence of cholecystolithiasis.Conclusion Minimally invasive cholecystolithotomy is an effective method in the treatment of cholecystolithiasis.For patients with metabolism syndrome,minimally invasive cholecystolithotomy should be used with caution or stone prevention drugs should be adopted after operation.