口腔感染及其并发症的药物防治策略

口腔感染最常见为草绿色链球菌、厌氧菌单独或混合感染,心瓣膜疾病、免疫损害及人工关节置入患者接受口腔手术后,若发生感染,则危害更大。该文回顾性分析了近年来有关口腔感染的药物敏感性研究,牙源性感染、非牙源性感染、口腔术后局灶性感染等的临床防治进展,以及肝、肾功能损害患者和孕妇等特殊患者的用药情况。

Antibiotic Use in Oral Infection and Its Complications

The most commonly isolated aerobic bacteria in postoperative bacteremia are streptococcus viridans and periodontal pathogenic anaerobic bacteria in blood cultures. Transient baeteremia is a known risk factor in the patients with altered immune system response and those with a susceptible site of infection. Antibiotics are indicated for odontogenic and oral non- odontogenic infections, as prophylaxis against focal infection, and as prophylaxis against local and systemic infection. Pregnancy, kidney and liver functional lesion are situations requiring special caution when indicating antibiotic treatment.