甲状腺肿物的临床、病理及超微病理的诊断分析

目的 通过分析甲状腺外科手术术患者的临床与病理又超微病理检查结果，了解甲状腺疾病的电镜诊断价值。方法 回顾2年中甲状腺肿物手术切除术患者80例，常规病理学检查以及电镜诊断的结果。根据滤泡上皮超微结构判断肿物病理性质。结果 临床诊断与病理诊断符合率低。光、电镜的病理诊断相符者78例；不相符者2例，光镜诊为甲状腺腺瘤，电镜诊为甲状腺癌。结论 甲状腺疾病的电镜检查，可了解滤泡上皮在不同疾病时的病变，修正病理学诊断的 错误，对于疾病的确诊具有重要的价值。

A comparative study of clinical pathological and electromicroscopic diagnosis for thyroid mass

Objective　To elucidate the value of electromicroscopy (EM) in the diagnosis of thyroid mass.　Methods　The diagnosis made by EM based mainly on the ultrastructural morphology of thyroid follicular epithelia (UMTFE) was compared with preoperative clinical diagnosis and diagnosis of routine pathology on 80 cases undergoing thyroidectomy for their thyroid mass.　Results　There were low rates of agreement between clinic and pathological diagnoses. The diagnostic results of 78 cases were consistent between light and electron microscopic examinations. However, there were two cases in which the diagnosis of thyroid adenoma based on light microscopy was corrected to thyroid carcinoma by electron microscopy.　Conclusion　Based on the observation for UMTFE electromicroscopy corrects the diagnostic error of routine pathology and helps in establishing a final correct diagnosis.