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指纹图谱在中药质量控制中的应用进展
引用本文:白瑞,王真真.指纹图谱在中药质量控制中的应用进展[J].安徽医药,2009,13(12):1458-1462.
作者姓名:白瑞  王真真
作者单位:安徽省马鞍山市药品检验所,安徽,马鞍山,243000;浙江大学药学院,浙江,杭州,310058
摘    要:本文综述了化学指纹图谱、生物指纹图谱及代谢指纹图谱在中药质量控制研究中的应用。化学指纹图谱已经发展比较成熟,并广泛应用于中药及其制剂的定性、定量研究中;生物指纹图谱和代谢指纹图谱与中药的药效活性相关,其发展尚处于起步阶段,但已经越来越受到人们的重视;建立从原料、中间体到制剂的包括化学与药效学信息的多维多息指纹图谱已经成为解决中药目前"信任危机"最有效的手段。

关 键 词:化学指纹图谱  生物指纹图谱  代谢指纹图谱  中药  质量控制

Application of fingerprint in the quality control of traditional Chinese medicine
BAI Rui,WANG Zhen-zhen.Application of fingerprint in the quality control of traditional Chinese medicine[J].Anhui Medical and Pharmaceutical Journal,2009,13(12):1458-1462.
Authors:BAI Rui  WANG Zhen-zhen
Institution:BAI Rui1,WANG Zhen-zhen2 (1.Maanshan Institute for Drug Control,Maanshan 243000,China,2.College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China)
Abstract:The application of the chemical fingerprint,biological biometric fingerprint and metabolic fingerprint in the quality control of traditional Chinese medicine research is reviewed in this paper.Among these,chemical fingerprint has been well developed and widely used in qualitative and quantitative research of Chinese medicine and its preparations.Biological fingerprint and metabolic fingerprint are related to the activities of traditional Chinese medicine.Although its development is still in the initial stag...
Keywords:chemical fingerprint  biological biometric fingerprint  metabolic fingerprint  traditional Chinese medicine  quality control  
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