应用超选择动脉灌注化疗治疗残胃复发癌

目的：评价超选择靶区动脉置泵灌注化疗治疗晚期残胃复发癌的疗效。方法：对我院经术中证实不能手术切除的18例残胃复发癌，术中超选择靶区动脉置泵，术后灌注化疗的疗效进行分析。结果：化疗后，临床症状均有不同程度的改善，肿瘤病灶完全缓解1例，部分缓解13例，稳定2例，恶化2例，有效率为77．8％，肿瘤细胞病理学改变有效率为83．3％，0．5，1．0，1．5，2．0年生存率分别为94．4％，66．7％，50．0％和27．8％，结论：超选择动脉灌注化疗是治疗晚期残胃复发癌的有效方法，可以明显延长患者的带癌生存期。

Superselective intra-arterial infusion chemotherapy for recurrent cancer in the remnant stomach after partial gastrectomy]

OBJECTIVE: To investigate the effect of superselective intra-arterial infusion chemotherapy in the treatment of advanced recurrent cancer in the remnant stomach after previous partial gastrectomy. METHODS: Eighteen patients with advanced recurrent cancer in the remnant stomach that were non-resectable as confirmed in the operations were included in this study, who subsequently received superselective intra-arterial infusion chemotherapy. RESULTS: Improvement of the symptoms to various degrees were achieved in all patients after the therapy, with the total rate of tumor reduction of 77.8% and pathologically confirmed improvement rate of 83.3%. The 0.5-, 1.0-, 1.5- and 2.0-year survival rates were 94.4%, 66.7%, 50.0% and 27.8% respectively. CONCLUSION: Superselective catheterization is effective in treatment of advanced recurrent cancer in the remnant stomach, which can significantly prolong the tumor-bearing survival period of the patients.