颅脑损伤并发中枢性低钠血症诊治分析

 目的 总结分析颅脑损伤并发中枢性低钠血症的临床特点 .方法 回顾性分析我科近5年收治的832例颅脑损伤患者临床资料. 结果 本组10例符合抗利尿激素分泌异常综合征,其中治愈8例,死亡2例 ;15例颅脑损伤符合脑性盐耗综合征,治愈13例,死亡2例.结论 颅脑损伤并发抗利尿激素分泌异常综合征的发病机制与治疗措施不同于脑性盐耗综合征,对其进行早期诊治能降低颅脑损伤患者的致残率和病死率.

Clinical analysis of craniocerebral injury complicated by central hyponatremia

Objective To study the clinical features of craniocerebral injury complicated by central hyponatremia. Methods The plasma osmolalitys and electrolyte content, and urine osmolality and electrolyte content in 832 patients with craniocerebral injury hospitalized in the past five years were analysed retrospectively. Results Syndrome of inappropriate antidiuretic hormone was found in 10 patients, of whom eight were cured and two died.Cerebral salt wasting syndrome was found in 15 patients,of whom 13 were cured and two died. Conclusions Pathogenesis and management of syndrome of inappropriate antidiuretic hormone complicating craniocerebral injury are different from those of cerebral salt wasting syndrome. Early diagnosis and treatment will reduce its disability rate and fatality rate.