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Oral intake of morphine in selectively bred rats
Authors:K. Paul Satinder
Affiliation:Department of Psychology, Lakehead University, Thunder Bay, Ontario, Canada
Abstract:Oral intake of morphine was investigated in selectively bred strains of rats. It was possible to induce all the five genetic lines to consume morphine in distilled water. Withdrawal of morphine resulted in significant decrease in the body weights of all the genetic lines in both the experiments. Significant drug-preference behavior was found only in three genetic lines with a common characteristic of relatively high emotional reactivity as compared to the two lines not showing such a behavior.
Keywords:Oral intake of morphine  Strain differences in morphine intake  Morphine withdrawal effects
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