Craniofacial and dental manifestations of triple X syndrome associated with congenital hypothyroidism: a case report |
| |
| Authors: | Kívia Linhares Ferrazzo DDS PhD Marcia Rodrigues Payeras DDS PhD Vilmar Antonio Ferrazzo DDS PhD Maurício Barbieri Mezomo DDS MS |
| |
| Affiliation: | 1. Professor of Oral Medicine, School of Dentistry, Franciscan University Center, , Santa Maria/Rio Grande do Sul, Brazil;2. Professor of Oral Pathology, School of Dentistry, Franciscan University Center, , Santa Maria/Rio Grande do Sul, Brazil;3. Professor of Orthodontics, School of Dentistry, Federal University of Santa Maria, , Santa Maria/Rio Grande do Sul, Brazil;4. Professor of Orthodontics, School of Dentistry, Franciscan University Center, , Santa Maria/Rio Grande do Sul, Brazil |
| |
| Abstract: | Triple X syndrome (47,XXX) is a numerical chromosomal alteration that affects 1/1,000 women, in which the woman is born with an extra X chromosome. Some oral changes have been reported in the literature, as hypodontia, influence on deposition of crown enamel and discrepancies in cephalometric measurements. Other systemic complications may lead to oral abnormalities similar to those seen in triple X patients, such as congenital hypothyroidism (CH). This paper reports a triple X syndrome case associated with CH later treated. Besides delay in cognitive and intellectual development, the patient had changes in teeth development and in cephalometric measurements with deficiencies in the maxilla and mandible. This is the first report of a triple X syndrome associated with CH. Both conditions may result in changes in dentofacial development. |
| |
| Keywords: | dental changes triple X syndrome 47 XXX congenital hypothyroidism craniofacial features |
|
|
