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Loss of nuclear TDP‐43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones |
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| Authors: | Joeri A Jansweijer Philip S Webb Channa A Hewamadduma Paul R Heath Adrian Higginbottom Rohini Raman Laura Ferraiuolo Johnathan Cooper‐Knock Christopher J McDermott Stephen B Wharton Paul G Ince |
| Institution: | 1. MRC Centre for Developmental and Biomedical Genetics, Firth Court, University of Sheffield, , Sheffield, UK;2. Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, , Sheffield, UK;3. Academisch Medisch Centrum, , Amsterdam, The Netherlands |
| Abstract: | |
| Keywords: | amyotrophic lateral sclerosis microarray mRNA post mortem splicing TDP‐43 |