Lymphocele after pediatric kidney transplantation: Incidence and risk factors |
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Authors: | Stefano Giuliani Piergiorgio Gamba Rim Kiblawi Paola Midrio Giulia Ghirardo Giovanni F Zanon |
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Institution: | 1. Department of Pediatric & Neonatal Surgery, St George's Healthcare NHS Trust and University, , London, UK;2. Division of Pediatric Surgery, Department of ‘Salute della Donna e del Bambino’, University of Padova, , Padova, Italy;3. Division of Pediatric Nephrology, Department of ‘Salute della Donna e del Bambino’, University of Padova, , Padova, Italy |
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Abstract: | Lymphocele is a well‐known postoperative complication after kidney transplantation. The aim of this study was to analyze time trend incidence, risk factors, and outcome of post‐transplant lymphocele in a large pediatric cohort. This is a retrospective single institution review of 241 pediatric kidney transplants performed from 2000 to 2013. Etiology of end‐stage renal disease, recipient age and gender, transplant year, BMI percentile for age, type of dialysis, living/non‐living related donor, acute rejection, and multiple transplantations were analyzed in association with lymphocele formation. Fourteen of 241 (5.81%) children developed a postoperative lymphocele. There has been a reduction in the incidence of lymphocele after 2006 (3.22% vs. 8.55%, p < 0.05). Significant risk factors for lymphocele were older age (≥11 yr), transplant before 2006, male gender, BMI percentile for age ≥95%, and multiple transplantations (p < 0.05). The one‐yr graft survival was significantly reduced in the group with lymphocele compared with control (81.2% vs. 92.51%, p < 0.04). This is the first pediatric report showing the following risk factors associated with post‐transplant lymphocele: age ≥11 yr, male gender, BMI for age ≥95%, and multiple transplantations. A lymphocele can contribute to graft loss in the first‐year post‐transplant. |
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Keywords: | lymphocele pediatric kidney transplantation |
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