北京市体检人群血尿酸增高率及相关因素分析

目的分析北京市健康体检人群血尿酸增高检出率及相关危险因素。方法对2008年至2012年258 452例健康体检者的血尿酸增高的分布情况进行分析,并抽取2012年66 333例健康体检者的血尿酸、体质量、血脂、血压和血糖资料进行分析,按血尿酸值分为尿酸增高组和尿酸正常组,比较不同年龄段两组体质量、血脂、血压和血糖异常检出率。结果北京市体检人群尿酸增高率男性为21.8%~27.2%,女性为5.5%~7.9%。男女比较差异有统计学意义(P<0.05)。尿酸增高组的超重肥胖、血脂异常、血压增高和血糖升高检出率均高于尿酸正常组,两组比较差异有统计学意义(P<0.05)。多因素Logistic回归分析显示超重肥胖、血脂异常、血压增高和血糖升高是尿酸增高的危险因素。结论北京市健康体检人群的男性尿酸增高的检出率较高,年轻女性尿酸增高检出率逐年攀升,应加强尿酸增高人群的健康管理工作,以有利于疾病的早期发现与诊治。

Analysis on relationship between blood uric acid increasing rate and the related risk factors in the physical examination's population in Beijing

Objective To analyse blood uric acid increasing rate and related risk factors of physical examination population Beijing. Methods The research was performed by analyzing blood uric acid increasing distribution from 258 452 health check-up participants in 2008-2012. Then we chose blood uric acid, body mass index(BMI), lipid, blood pressure and fasting blood glucose subjects in 66 333 physical examinationparticipants in 2012. According to the blood uric acid values the experiments were divided into increased uric acidgroup and uric acid in normal ones. To compare with those two group''s abnormal detection rate on BMI, lipid, blood pressure, blood glucose by different age groups. Results The prevalence of uric acid increased rates were 21.8%-27.2% in male and 5.5%-7.9% in female. The comparative difference has statistical significance(P<0.05). The overweight, obesity, dyslipidemia, blood pressure and blood glucose abnormal detection rate of the uric acid group are all higher than those of the normal uric acid group(P<0.05). Multivariate logistic regression analysis shows overweight obesity,dyslipidemia, hyperuricemia and hyperglycemia are the risk factors for hyperuricemia. Conclusion In all of the participants, the blood uric acid increasing detected rate in male is higher. Then younger female''s uric acid detected rate annually increased. Therefore the health management for the population with blood uric acid increasing should be strengthened for the early detection, diagnosis and treatment of the disease.