| 三氧化二砷注射液治疗中晚期原发性肝癌15例报告 |
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| 引用本文： | 陈峰,陈晓耕.三氧化二砷注射液治疗中晚期原发性肝癌15例报告[J].现代肿瘤医学,2005,13(5):665-666. |
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| 作者姓名： | 陈峰 陈晓耕 |
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| 作者单位： | 福建省立医院肿瘤科,福建,福州,350001 |
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| 摘 要： | 目的 评价三氧化二砷（As2O3）治疗中晚期原发性肝癌的近期疗效和不良反应。方法 中晚期原发性肝癌共15例，采用单药三氧化二砷（As2O3）静脉滴注10mg/d,连续10天为1周期,间歇3周重复。结果 PR 3例,NC 8例,PD 4例，有效率20%,主要的不良反应为轻度的骨髓抑制和肝功能损害。结论 三氧化二砷（As2O3）治疗中晚期原发性肝癌确实有效,不良反应少,值得推广。
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| 关 键 词： | 三氧化二砷（As2O3） 药物治疗 原发性肝癌 |
| 文章编号： | 1672-4992-（2005）05-665-02 |
| 收稿时间： | 2005-04-20 |
| 修稿时间： | 2005年4月20日 |
The clinical study of arsenic trioxide in the treatment of advanced primary liver cancer |
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| CHEN Feng,CHEN Xiao-geng.The clinical study of arsenic trioxide in the treatment of advanced primary liver cancer[J].Journal of Modern Oncology,2005,13(5):665-666. |
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| Authors: | CHEN Feng CHEN Xiao-geng |
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| Abstract: | Objective To evaluate the effect and toxicity of arsenic trioxide(As_2O_3)in treatment of advanced primary liver cancer. Methods Fifteen cases with advanced primary liver cancer were treated with As_2O_3 injection only, at single dose of 10mg/d by venous instillation, using 10 days continuously and repeated after 3 weeks. Results PR was got in 3 cases, NC 8 cases and PD 4 cases. Total response rate was 20%. The major adverse reactions were mild bone marrow suppression and hepatic function damage. Conclusion As_2O_3 is effective to treat advanced primary liver cancer, the adverse reactions are mild. |
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| Keywords: | As2O3 drug treatment primary liver cancer |
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