| 曲马多对异氟醚的MAC和循环的影响 |
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| 引用本文： | 杨军良,赵砚丽.曲马多对异氟醚的MAC和循环的影响[J].中华麻醉学杂志,1994,14(2):96-98. |
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| 作者姓名： | 杨军良 赵砚丽 |
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| 作者单位： | 河北省医院麻醉科!石家庄市，邮政编码050071，河北省医院麻醉科!石家庄市，邮政编码050071，河北省医院麻醉科!石家庄市，邮政编码050071 |
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| 摘 要： | 观察４１例患者应用曲马多后对异氟醚ＭＡＣ的影响及对血液动力学的影响。静滴曲马多２ｍｇ／ｋｇ，在３１～５５岁组和≥５６岁组患者的异氟酸ＭＡＣ值分别为１.０７％和０.９６％，静滴曲马多４ｍｇ／ｋｇ，在这两个年龄组异氟醚ＭＡＣ值分别为０．９８％和０．９０％。和基础值相比，静滴由马多４ｍｇ／ｋｇ后患者心率和血压分别增加 ２３． ５％（Ｐ＜０． ００１）和 ７． ７％（Ｐ＜０． ００１）， １０分钟后 Ⅱ组患者的心率和血压均显著高于Ⅰ组（Ｐ<０．０２和０．００２）。结果表明，曲马多可强化吸入麻醉药，大剂量时还有明显的循环效应。
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| 关 键 词： | 曲马多 异氟醚 MAC 血流动力学 |
The effects of tramadol on the minimum alveolar concentration(MAC) of isoflurane and on the hemodynamics |
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| Yang Junliang,Zhao Yan li,Chen Boluan..The effects of tramadol on the minimum alveolar concentration(MAC) of isoflurane and on the hemodynamics[J].Chinese Journal of Anesthesilolgy,1994,14(2):96-98. |
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| Authors: | Yang Junliang Zhao Yan li Chen Boluan |
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| Abstract: | In 41 unpremeditated ASA adult patients we investigated the effects of tramadol on the minimum alveolar concentration (MAC ) of isoflurane and on the patient's heart rate (HR ) and mean blood pressure (MAP). The MAC was assessed by the "modified up-and -down method"of Dixon. In pa tients at ages 31 -55 years and years ad ministered with tramadol 2mg/kg,the MAC of isoflurane were 1. 07% and 0. 96%, and with tramadol 4mg/kg, were 0. 98% and 0. 90%. Following injection of tramadol 4mg/kg, the patients'HR and MAP increased by 23. 5% (P < 0. 001 ) and 7. 7 % (P< 0. 001 ) respectively compared with baseline values. At 10 minuts after administration of tramadol, the HR and MAP in patients with 4mg/kg were higher than those with 2mg/mg(P
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| Keywords: | Tramadol Isoflurane MAC Hemodynamics |
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