| 乳酸中毒和pH对狗肺血管张力和气体交换功能影响的实验研究 |
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| 引用本文： | 黄宇光 叶宏轩. 乳酸中毒和pH对狗肺血管张力和气体交换功能影响的实验研究[J]. 中华麻醉学杂志, 1994, 14(6): 413-415 |
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| 作者姓名： | 黄宇光 叶宏轩 |
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| 作者单位： | 北京协和医院麻醉科!邮政编码100730(黄宇光)，台湾高雄医学院麻醉科(叶宏轩)，美国犹他大学医院麻醉学系(KCWong) |
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| 摘 要： | 急性代谢性酸中毒对狗血管张力和气体交换功能的影响进行了研究。当滴入乳酸或盐酸造成急性代谢性酸中毒（ｐＨ７．００）时，可引起肺血管收缩，肺动脉压力明显升高，血氧饱和度下降，并且乳酸和盐酸引起的酸中毒对肺动脉平均压影响程度相似，提示肺血管收缩和肺动脉压升高的程度与血中ｐＨ值下降关系密切，而与此时血中乳酸水平的高低无关。
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| 关 键 词： | 代谢性酸中毒 乳酸 盐酸 肺血管收缩 |
Influences of lactic acidosis and pH on pulmonary vasoconstriction and gas exchanges in dogs. |
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| Huang Yuguang, Ye Hongxuan, KC Wong,. Influences of lactic acidosis and pH on pulmonary vasoconstriction and gas exchanges in dogs.[J]. Chinese Journal of Anesthesilolgy, 1994, 14(6): 413-415 |
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| Authors: | Huang Yuguang Ye Hongxuan KC Wong |
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| Abstract: | The influences of lactic/hydrochloric acidosis on pulmonary vasoconstriction and gas exchanges were investigated in 36 dogs. The tv infusion of lactic or hydrochloric acid reducing arterial pH to 7. 00 could elicit significant changes of pulmonary hemodynamics, including the consistent increase of pulmonary arterial pressure and the decrease of arterial oxygen saturation. It is suggested that pulmonary vasocostriction is related to arterial PH but not to arterial lactic acid levels. |
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| Keywords: | Metabolic acidosis Lactic acid Hydr-ochloric acid Pulmonary vasoconstriction |
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