离体冠状动脉粥样硬化钙化斑块CT、MRI及病理对照

目的 评价64层CT和1.5T MR扫描仪在显示离体冠状动脉粥样硬化钙化斑块成分的作用.方法 对12具尸体心脏行冠状动脉前降支近段CT及MR检查,并与病理学相对照.分析钙化斑块的CT值及MRI的信号强度.结果 43个CT、MRI所示的钙化斑块层面可与相应的组织学层面相对应.钙化成分为主的斑块CT值平均为1065 HU.MRI示钙化斑块在各个序列均表现为低信号,48.84%的钙化层面内有稍高信号,组织切片示脂质成分.58.14%的钙化斑块内有新生血管或炎细胞浸润.结论 CT、MRI都可以显示冠状动脉粥样硬化钙化斑块的特点,但显示钙化斑块内的脂质成分,MRI优于CT.

CT and MRI of coronary atherosclerotic calcified plaques in vitro: Comparison with pathological findings

Objective To assess the value of 64-slice CT and MRI in demonstrating the component of coronary atherosclerotic calcified plaques in vitro. Methods Twelve consecutive autopsy hearts were examined after intubating into left main trunk successfully. Compared with pathological findings, the value of CT in calcified plaque was assessed, and the MR signals of lesions were analyzed. Results Forty-three histological sections were matched with CT and MRI. The mean CT value for calcified plaque was 1065 HU. Low signal on all of the pulse sequences represented calcified plaque. Slightly high signal on MRI representing lipid component could be detected in 48.84% calcified lesions. The neovascularization or inflammatory cells on histological sections were found in 58.14% calcified plaques. Conclusion CT and MRI can both display the features of coronary atherosclerotic calcified plaques. However, MRI is superior to CT for demonstrating the lipid component of calcified plaque.