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海杧果叶中有机酸类成分研究
引用本文:张小坡,裴月湖,刘明生,康胜利,张俊清. 海杧果叶中有机酸类成分研究[J]. 中草药, 2010, 41(11): 1763-1765
作者姓名:张小坡  裴月湖  刘明生  康胜利  张俊清
作者单位:海南医学院热带药用植物研究开发省重点实验室, 海南海口 571101;海南省南药黎药研究院, 辽宁沈阳 110016;海南省南药黎药研究院, 辽宁沈阳 110016;海南医学院热带药用植物研究开发省重点实验室, 海南海口 571101;沈阳药科大学中药学院, 海南海口 571101;海南医学院热带药用植物研究开发省重点实验室, 海南海口 571101;沈阳药科大学中药学院, 海南海口 571101;海南医学院热带药用植物研究开发省重点实验室, 海南海口 571101;沈阳药科大学中药学院, 海南海口 571101
摘    要:目的研究半红树植物海杧果Cerbera manghas叶中的有机酸类成分。方法通过多种柱色谱进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果 从海杧果叶中分离得到7个化合物,分别鉴定为间羧基苯乙酸(1)、对羟基苯甲酸(2)、原儿茶酸(3)、对羟基桂皮酸(4)、间羧基苯甲酸(5)、香草酸(6)、丁二酸(7)。结论化合物1为新天然产物,化合物2~6为首次从该属植物中分离得到。

关 键 词:海杧果  有机酸  间羧基苯乙酸
收稿时间:2010-02-14

Organic acids from leaves of Cerbera manghas
ZHANG Xiao-po,PEI Yue-hu,LIU Ming-sheng,KANG Sheng-li and ZHANG Jun-qing. Organic acids from leaves of Cerbera manghas[J]. Chinese Traditional and Herbal Drugs, 2010, 41(11): 1763-1765
Authors:ZHANG Xiao-po  PEI Yue-hu  LIU Ming-sheng  KANG Sheng-li  ZHANG Jun-qing
Affiliation:Hainan Provincial Key Laboratory of R & D of Tropical Herbs, Haikou 571101, China;School of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;School of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;Hainan Provincial Key Laboratory of R & D of Tropical Herbs, Haikou 571101, China;Hainan Provincial Institute of South China Medicine and Li Nationality Medicine, Haikou 571101, China;Hainan Provincial Key Laboratory of R & D of Tropical Herbs, Haikou 571101, China;Hainan Provincial Institute of South China Medicine and Li Nationality Medicine, Haikou 571101, China;Hainan Provincial Key Laboratory of R & D of Tropical Herbs, Haikou 571101, China;Hainan Provincial Institute of South China Medicine and Li Nationality Medicine, Haikou 571101, China
Abstract:Objective To study the organic acids in the leaves of Cerbera manghas.Methods The con-stituents were isolated by repeated column chromatography and their structures were elucidated on basis of physico-chemical constants and spectral data analyses.Results Seven compounds were obtained and determined to be m-carboxyphenylacetic acid(1),p-hydroxybenzoic acid(2),protocatechuic acid(3), p-hydroxycinnamic acid(4),isophthalic acid(5),vanillic acid(6),and succinic acid(7).Conclusion Compound 1 is a new natural product,compounds 2-6 are obtained from the plants of Cerbera L.for the first time.
Keywords:Cerbera manghas L.  o rganic acids  m-carboxypheny lacetic acid
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