脂肪酸结合蛋白在急性心肌梗死患者早期诊断中的应用研究

目的探讨脂肪酸结合蛋白在急性心肌梗死(AMI)患者早期诊断中的应用价值。方法选取AMI患者60例根据胸痛到就诊时间不同分为4h组及4～8h组。对全部患者于就诊时即刻抽血检测心肌肌钙蛋白I(cTnI),肌酸激酶同工酶(CK-MB)及心脂肪酸结合蛋白(H-FABP),计算3种检测指标对两组患者诊断的特异度。结果两组患者在4h组的cTnI、CK-MB与H-FABP特异度差异对比有统计学意义(P<0.05)。结论 H-FABP在AMI早期诊断中特异度优于cTnI、CK-MB。

The applied value of fatty acid binding protein in early diagnostic of acute myocardial infarction(AMI)

Objective To investigate the applied value of fatty acid binding protein in early diagnostic of acute myocardial infarction(AMI).Methods Sixty patients with AMI were selected according to the different time of chest pain and they were devided into 4 h groups and 4-8 h groups.All patients in hospital were given immediate blood detection of myocardial troponin I(cTnI),creatine kinase(CK-MB)and heart fatty acid binding protein(H-FABP).Then calculate the influence of this three detection to the specificity of two groups.Results Compared the specificity of cTnI,CK-MB with H-FABP differences had statistically significant(P<0.05)in four hours group.Conclusion H-FABP in the early diagnosis of AMI specificity is superior to cTnI,CK-MB.