高压氧治疗血管性痴呆神经心理学与事件相关电位的研究

目的探讨高压氧治疗血管性痴呆神经心理学与事件相关电位 (P30 0 )的变化规律及临床意义。方法选取血管性痴呆患者 3 0例观察高压氧治疗与一般治疗前后 ,用认知能力甄别检查法 (CCSE)、老年性痴呆评定量表 (ADAS)作神经心理学测试后 ,再做听觉Oddball序列研究血管性痴呆患者事件相关电位 (ERPs)的P3成分进行相关比较分析。结果高压氧 (HBO)治疗血管性痴呆的CCSE、ADAS有显著差异 (P <0 .0 5 ) ,P3潜伏期 (P3PL) ,P3波幅 (P3AMP)差异显著 (P <0 .0 5 )。结论高压氧治疗后血管性痴呆的认知功能评分与P3潜伏期有明显的改善

Study of Correlation between Neuropsychology and Event-related Potentials after Hyperbaric Qxygen Therapy in Angiodementia

Objective To explore the correlation between angiodementia neurtopsychology and ERPs and its clinical significance.Methods 30 cases with angiodementia were selected as a patient group and 30 normal subjects with corresponding age and sex as a control group.At first,neuropsychological examinations were made with CCSE and ADAS,then the component P 3 of ERPs of the patients with angiodementia was studied by acuesthesia Oddball sequencing and then correlative analyses were incluted.Results The disparity between the two groups is notable(P<0.05)after hyperbaric oxygen therapy.P 3PL and P 3AMP in the patient group were much different from those in the control group(P<0.05).Conclusion Hyperbaric oxygen is an effective method to evaluate the cognitive function of patients with angiodementia.It also has curative effect for the P 3PL patients.