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胸液P-选择素检测对结核性与恶性胸腔积液鉴别意义的探讨
引用本文:赵云峰,王英年,高岱清,张春玲,马学真,吴学玲,刘加洪.胸液P-选择素检测对结核性与恶性胸腔积液鉴别意义的探讨[J].中国防痨通讯,2002,24(4):200-202.
作者姓名:赵云峰  王英年  高岱清  张春玲  马学真  吴学玲  刘加洪
作者单位:青岛大学医学院第二附院 青岛 266042;
摘    要:目的 检测结核性及恶性胸腔积液患者胸液P-选择素水平,探讨其对鉴别良恶性疾病的意义。方法 采用酶联免疫吸附法(ELISA法)检测48例结核性胸液及50例恶性胸液P-选择素水平。结果 恶性胸液P-选择素水平(18.76±8.45μg/L)明显高于结核性胸液P-选择素(7.43±5.32μg/L)(P<0.01)。结论 测定胸液P-选择素水平有助于结核性及恶性胸液的鉴别。

关 键 词:P-选择素  胸腔积液  酶联免疫吸附试验  
修稿时间:2001年6月25日

Significance of detecting P-selectin of pleural effusion in differentiating tuberculous and malignant pleural effusions
ZHAO Yun feng,WANG Ying nian,GAO Dai qing,et al..Significance of detecting P-selectin of pleural effusion in differentiating tuberculous and malignant pleural effusions[J].The Journal of The Chinese Antituberculosis Association,2002,24(4):200-202.
Authors:ZHAO Yun feng  WANG Ying nian  GAO Dai qing  
Institution:The Second Affiliated Hospital of Qingdao University Medical College,Qingdao 266042
Abstract:Objective To explore the clinical significance of detecting P-selectin of pleural effusions in differentiating tuberculous and malignant diseases.Methods To detect the content of P-selectin in centrifuged supernatant of 48 cases with tuberculous pleural effusions and 50 cases with malignant pleural effusions by ELISA method.Results P-selectin of malignant pleural effusions (18.76±8.45μg/L) was distinctly higher than that of tuberculous pleural effusions (7.43±5.32μg/L) (P<0.01).Conclusion Detecting P-selectin of pleural effusion might be helpful for differentiating tuberculous and malignant diseases.
Keywords:P-selectin  Pleural effusion  Enzyme-linked immunosorbent assay  
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