Procalcitonin may help differentiate disseminated herpes simplex viral infection from bacterial sepsis in neonates |
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| Authors: | M Hatherill K Sykes A G McIntyre I A Murdoch |
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| Institution: | (1) Paediatric Intensive Care Unit, Guy's Hospital, St. Thomas' Street, London SE1 9RT, UK Tel.: +44-171-955-2564; Fax: +44-171-955-2563, GB |
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| Abstract: | Disseminated herpes simplex virus infection is a potentially fatal condition which may be difficult to differentiate from
bacterial sepsis. We report the case of a neonate with overwhelming herpes simplex (type 2) viraemia who presented with `septic
shock'.
Conclusion A low procalcitonin level (1.6 ng/ml), inconsistent with bacteraemia, suggests an alternative aetiology and may strengthen
the case for antiviral therapy.
Received: 28 March 1999 / Accepted: 10 August 1999 |
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| Keywords: | AbbreviationsHSV herpes simplex virus PCT procalcitonin |
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