冰冻单采血小板在治疗弥散性血管内凝血中的疗效

目的研究冰冻单采血小板在治疗弥散性血管内凝血（DIC）的疗效。方法将48例DIC患者随机分成两组：26例输注冰冻单采血小板,22例输注新鲜单采血小板。测定两组患者输前1h和输后2h指标：①凝血酶时间（TT）;②活化部分凝血活酶时间（APTT）;③凝血酶原时间（PT）;④纤维蛋白原（Fbg）;⑤血小板（PLT）。结果输注冰冻单采血小板组与输注新鲜单采血小板组输后2h比较：TT、PT、APTT及Fbg差异无统计学意义（P〉0.05）,PLT显著减少（P〈0.05）。结论冰冻单采血小板在治疗DIC时具有较佳的止血疗效。

Therapeutic Effects of Frozen Platelets on the Treatment of Bleeding Caused by Disseminated Intravascular Coagulation

Objective To evaluate the efficacy of using frozen platelets for treating patients with disseminated intravascular coagulation(DIC). Methods 48 patients with DIC were grouped randomly into two groups. 26 patients received frozen platelets,and 22 patients received fresh platelets. Various parameters,namely the thrombin time (TT),activated partial thromboplasting time (APTT),prothrombin time (PT),fibrinogen (Fbg),and platelet (PLT) were examined at 1 hour before and 2 hours after transfusion. Results With the exception of PLT,significant differences in TT,PT,APTT and Fbg were not observed between the two groups of patients(P>0.05). Conclusion Frozen platelets may be used in the patients with DIC.